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128 To further expand the chemical diversity of the genetic code to include new classes of monomers, recently Jason Chin’s lab 160 has introduced a novel technique tRNA display to identify orthogonal synthetases that are capable of acylating their corresponding orthogonal tRNA with a range of eight ncAAs and eight different ncMs, including a variety of β-amino acids, α,α-disubstituted-amino acids, and β-hydroxy acids, thereby facilitating the genetic encoding β-amino acids and α,α-disubstituted amino acids into proteins and the encoded synthesis of noncanonical polymers and peptide-like products